Inhibition of hepatitis B virus assembly with synthetic peptides derived from the viral surface and core antigens.
نویسندگان
چکیده
منابع مشابه
Inhibition of hepatitis B virus assembly with synthetic peptides derived from the viral surface and core antigens.
The long surface antigen (L-HBsAg) of hepatitis B virus (HBV) plays a central role in the production of infectious virions. During HBV morphogenesis, both the PreS and S domains of L-HBsAg form docking sites for the viral nucleocapsids. Thus, a compound that disrupts the interaction between the L-HBsAg and nucleocapsids could serve as a therapeutic agent against the virus based upon inhibition ...
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ژورنال
عنوان ژورنال: The Journal of General and Applied Microbiology
سال: 2002
ISSN: 0022-1260,1349-8037
DOI: 10.2323/jgam.48.103